Scientist reveals possible cure for Ebola Virus – Bitter Kola to the rescue?

EbolaA plant has been found to halt the deadly Ebola virus in its tracks in laboratory tests, scientists have said. They used a compound from Garcinia kola, a plant commonly eaten in West Africa. Compounds from the plant have also proved effective against some strains of flu. If the anti-Ebola compound proves successful in animal and human trials, it will be the first medicine to successfully treat the virus that causes Ebola haemorrhagic fever – an often-fatal condition.

The discovery was announced at the 16th International Botanical Congress in St Louis in the US.

Traditional origins

Dr Maurice Iwu, who set up and heads the Bioresources Development and Conservation Programme, led the research.

It started 10 years ago when researchers were led to the plant by traditional native healers who have used the plant for the treatment of infectious diseases for centuries.

“This is a very exciting discovery,” said Dr Iwu, who himself comes originally from a family of traditional healers.

“The same forest that yields the dreaded Ebola virus could be a source of the cure.”

The Nigerian researchers claim they are a step closer to a universally accepted cure for Ebola virus, Dengue fever and leishmaniasis. They claim the herbal preparation has also been successfully used, in clinical studies, to treat hepatitis B and C, cancer, diabetes and tuberculosis.

The researchers from Halamin Herbal centre, 10 George Innih Crescent, Apo District, Abuja and Department of Histopathology and Cytology, Jos University Teaching Hospital (JUTH) Jos, Plateau State, found that the poly herbal preparations- DAABS2 and HEPATOSAAB- strengthen the immune system through many cytokines and chemokines regulations.

Amodu is also a member of the committee inaugurated by the Director General of the National Agency for Food Drug Administration and Control (NAFDAC), Dr. Paul Orhii, to champion the development of herbal medicine through scientific validation of all the cure claims.

The yet to be published new study is titled “Natural and Sustainable Alternative for the Management of Dengue Fever in West Africa.”

Also results of another study presented, in 1999, at the 16th International Botanic Congress in St Louis, Missouri, United States, indicate that bitter cola (Garcinia kola), a plant widely used in traditional African medicine may contain a compound that is effective against Ebola virus disease.

Executive director of the Bio-resources Development and Conservation Programme, Prof. Maurice Iwu, explained that an extract derived from the seeds of Garcinia kola could inhibit this virus in cell culture at non-toxic concentrations.

Iwu and his colleagues identified Garcinia kola as a possible source of drugs using the method called Corbel (clinical observation-based ethnomedical lead).

Extracts from Garcinia kola seeds were tested against many complex viral diseases. The active compound, now known to be a biflavonoid, was found to be active against a wide range of viruses including the influenza virus.

Iwu reveals last week: “The active substance is an extract from Garcinia kola (bitter kola) called Kolaviron, which contains bioflavonoids and prenylated xanthones and benzophenones.
“Work was done while a scientist at the Division of Experimental Therapeutics of Walter Reed Army Institute of Research Washington DC in collaboration with Southern Research Institute (SRI).

“But no follow up. Others at Ibadan and other Nigerian universities have done follow-up work on Kolaviron.”

Fighting chance

The virus multiplies rapidly in the human body and quickly overwhelms it, and in advanced cases the patient develops high fever and severe bleeding.

The Garcinia kola compound has been shown to halt multiplication of the virus in the laboratory. If repeated in humans, this would give the body a chance to fight off the virus.
The active compound is what is known as a dimeric flavonoid, which is two flavonoid molecules fused together.

Flavonoids are non-toxic and can be found in orange and lemon rinds as well as the colourings of other plants.

Drug hopes

The tests are in the early stages still, but the researchers hope that if they continue to prove successful the compound the US Food and Drug Administration will put it on a fast track – making a drug available to humans within a matter of years.

“The discovery of these important properties in a simple compound – flavonoids – was very surprising,” said Dr Iwu.
“The structure of this compound lends itself to modification, so it provides a template for future work.

“Even if this particular drug does not succeed through the whole drug approval process, we can use it to construct a new drug for this deadly disease.”

The Ebola virus was first documented in 1976 after an outbreak in Zaire, now the Democratic Republic of the Congo – where 88% of the 318 human cases died.

More recently, a 1995 outbreak in the same country had a death rate of 81% of the 315 infected.

There are four types of the virus – Ebola-Zaire, Ebola-Sudan and Ebola-Ivory Coast all affect humans, while Ebola-Reston has so far only affected monkeys and chimpanzees.

However, doctors have been unable to stop the virus once infection has taken hold – hence the disease has gained a terrifying reputation.

 

_411030_dr_maurice_iwu150

(Pictured above) Dr Maurice Iwu, who set up and heads the Bioresources Development and Conservation Programme, led the research.

 

Culled from: BBC

 

Advertisements

30/07/2014 ~ #NicholasA ~ 15 Success Habits You Need To Develop. RESPONSE.

zebra-on-a-bike-lion

“Leave your excuses and live your dreams” ~ Paul Davis.

Over the past 9 days we have been on the series that focuses on the success habits every success-minded individual need to develop and I have been getting interesting feedbacks and comments. Thanks for following my daily posts. If at anytime you miss any of my post or you want to read any previous one, you can always find them on www.nicholasae.blogspot.com or www.nic4bags.wordpress.com. I will love to get your comments and contributions because I know you have a lot to share.

One of my ardent followers buzzed with a concern on success. His questions was how does the general adage “No hurry in life and slow and steady wins the race” connect to the issue of time in yesterday’s post? I am going to try and address this today.

While I was growing up, there was one popular proverb we played with in school, it says “Because the hunter has learnt to shoot without missing, birds have learnt to fly without perching”.

We must understand that life is evolving, things are changing, they are not as it used to be.

When people say no hurry in life, it does not mean you should be slow in your growth or pursuit of your dreams, neither does it mean you cannot fly if you have the ability to. You do not tell a child who just started walking to continue crawling because you feel he is too small to walk, if his bones can sustain him, he is good to go. What both advice (no hurry, slow & steady) mean is that get yourself prepared first for what you want to start cos’ if you don’t prepare enough and hurry it into, you will crash. That is the truth. But if you misunderstand them and you sit on your butt telling yourself that there is still time, am sorry to inform you, time waits for no man.  

A good illustration is the picture on my DP (if you are reading from BBM or Whatsapp). Ordinarily, the Zebra cannot outrun the Lion but with the motorcycle, he can. But if the Zebra decides to stick with the old method of running with his legs, hmmm my guess is as good as yours.  

For every man and woman, your responsibilities and expectations increases and grow as you do. The amount of money needed to sustain you some years back is not the same today, it has doubled, tripled and even more. If your income still remains the same, then you will be in great trouble.

It is your level of success that determines how much income you take home at the end of the month. And you will agree with me that new inventions and possibilities are opening up every day. People want to be part of the new happenings, employers want to use the latest tools in the market hence they seek individuals with such skills, customers want to associate with businesses that integrate latest developments. If you want to increase your level of success you must decide to start walking in areas where you have been crawling, running where you have been walking and flying where you have been running.

Someone said “good things come to those who wait but better things come to those who go out and get them”.   

The world awaits you!

Please do leave your comments.

Have a lovely Wednesday!

I honour you.

#NicholasA

T: @ItsNicholasAE

G+: +NicholasAkomire

BBM: 7AAD4E7A

29/07/2014 ~ #NicholasA ~ 15 Success Habits You Need To Develop. #9 Spending Time and Energy on Fruitful Engagements.

time-management  If you love life, don’t waste time, for time is what life is made up of ~ Bruce Lee.

Of all the resources God has given to every man to create his or her own success, time is the most important. That is why the bible says “… but time and chance happeneth to them all…Ecl. 9 : 11”.

The difference between a man who succeeds and the one who failed is how they spent their time and energy. You cannot get the best out of the thing you give the smallest time. You will agree with me that other than just the necessary ingredients, a nice meal needs quality time and attention during preparation. The same applies to that project, business, or dream of yours. If you want it to be successful, you need to give it quality time.

A great mistake we make at times is spending time on things that will not bring us closer to our dreams. No man running a marathon stops to give a handshake, it must wait till the finish line.  

Studying, building your business, associating with successful people are good ways to use these two precious resources – time and energy – to invite success. The more wisely you spend your time and energy, the more successful you become. 

Socrates once said “The secret of change is to focus all of your energy, not on fighting the old, but on building the new”. If you want something greater than what you already have, focus your time and energy on it.  

Time is an equal opportunity employer. Each human being has exactly the same number of hours and minutes every day. Rich people can’t buy more hours. Scientists can’t invent new minutes. And you can’t save time to spend it on another day. Even so, time is amazingly fair and forgiving. No matter how much time you’ve wasted in the past, you still have an entire tomorrow, don’t waste that as well ~ Denis Waitley.

I honour you!

#NicholasA

T: @ItsNicholasAE

G+: +NicholasAkomire

BBM: 7AAD4E7A

28/07/2014 ~ #NicholasA ~ 15 Success Habits You Need To Develop. #8 Finding Strength Within!

http://bit.ly/X3a8Ll

No one can make you feel inferior without your permission ~ Eleanor Rosevelt.

How you think and feel about yourself always clothes you with energetically similar reality. When you get in touch with your strong and authentic self, life’s difficulties don’t seem that discouraging anymore. You must understand that there will be times when things will not feel right, there will be times when you get discouraged and it seems you need a time out but life is not a video game with a pause button that you can hit and take a break, you have to keep going and to do that you need to look for the strength within you.

This is the time when you need to ask yourself these questions: Was I made to fit in or stand out? Am I here to watch or make things happen? Did I come this far to back out? Is there a slight chance that I can make it? If you can answer these questions, I believe you will find the strength you need.

The easiest way to connect with this inner core of strength is to read inspirational stories, because they help you understand that no matter where you are in life and no matter who you are, you can become as great as you choose to be.

Sometimes we forget about our own advantages because we focus in what we don’t have. Just because you have to work a little harder at something that seems easier to others don’t mean you’re without your own talents ~ Chris Colfer. Always remember that all men were not born equal.

May Sarton wrote “We have to dare to be ourselves, however frightening or strange that self may prove to be”.

You are the sole creator of your life – the sooner you understand this, the quicker you will feel empowered to change.

If you can’t fly then run, if you can’t run then walk, if you can’t walk then crawl, but whatever you do you have to keep moving forward ~ Martin Luther King Jr.

Have a fruitful week.

I honour you!

#NicholasA

T: @ItsNicholasAE

G+: +NicholasAkomire

 

BBM: 7AAD4E7A

27/07/2014 ~ #NicholasA ~ 15 Success Habits You Need To Develop. #7 Personal Integrity.

Talent without discipline is like an octopus on roller skates. There’s plenty of movement, but you never know if it’s going to be forward, backwards or sideways ~ Jackson Brown.
 
One of the most important value that people look for in an individual is integrity. People want to interact and have dealings with someone whose words and actions can be trusted, not an individual whose integrity is in doubt.
 
It is very important that what you said yesterday is the same thing that you will say today, tomorrow and any other day thereafter. Once people realize that you are inconsistent in your words and actions, they will withdraw from you and when that begins to happen, you are gradually losing your shot at success.
 
Always follow your heartfelt values, and never let a situation or anyone steer you away from doing what you know is right. Be someone that people can look up to and respect and not someone who trades his or her moral values for material gains in life.
 
You do not need to bend your moral value in order to win anyone.
 
Will Smith said “Don’t chase people. Be yourself, do your own thing and work hard. The right people – the ones who really belong in your life – will come to you and stay”.
 
Keep doing what is right, keep holding up your personal integrity, your success is not far away.
 
Have a wonderful Sunday celebration and thanksgiving.
 
I honour you!
 
#NicholasA
T: @ItsNicholasAE
G+: +NicholasAkomire
BBM: 7AAD4E7A

26/07/2014 ~ #NicholasA ~ 15 Success Habits You Need To Develop. #6 Value Yourself.

http://bit.ly/WUckor

Value Yourself
One of the most beautiful things God created is you, that’s why my friend @IamQueenVikcy wrote in her song…
“Did I hear you say, nothing special about me, did I hear you say, am not important, didn’t make you first so won’t sweat, made all things first so you will flex, oxygen from plant to you, nature works hand in hand for you, don’t you ever undermine my priceless craft that took my time, you should really know your worth, 24 hours nor be mouth, finger prints unique design there’s not the one that looks like yours, each time I look at you I find reasons to scream BEAUTIFUL……”
Walt Disney once wrote ~ The more you like yourself, the less you are likely anyone else, which makes you unique.
You must learn to appreciate YOU, It’s vital for your success.
Success can only come if you feel worthy of it. Most people don’t, because of their “not–dealt-with” past hurts. Whether these emotional pains were caused by parents’ discouragements, teachers’ close-minded criticisms or peers’ hurtful remarks, you should deal with them so that they would stop affecting your self-esteem.
The fact that you have come this far is a confirmation of your uniqueness, don’t undermine that.
Learn to behave like the male Lizard  as the African proverb would have it, who when he falls from a great height praises himself with a nod when no one else will.
Do celebrate yourself.
Have a great weekend!
I honour you!
#NicholasA
T: @ItsNicholasAE
G+: +NicholasAkomire
BBM: 7AAD4E7A